Analysis of glyphosate in residential dust samples and risk of childhood leukemia in the California Childhood Leukemia Study
Solicitation Number: N02RC62644-24
Agency: Department of Health and Human Services
Office: National Institutes of Health
Location: National Cancer Institute, Office of Acquisitions
Office: National Institutes of Health
Location: National Cancer Institute, Office of Acquisitions
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N02RC62644-24
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Presolicitation
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Added: Aug 19, 2016 1:42 pm
Contracting Office Address
Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 9609 Medical Center Drive, Room 1E226, Bethesda, MD 20892, UNITED STATES
Description
The National Cancer Institute (NCI), Division of Cancer Epidemiology and Genetics (DCEG), Occupational and Environmental Epidemiology Branch (OEEB) plans to procure services to measure the herbicide glyphosate in 89 homes from a case-control study of childhood leukemia (the California Childhood Leukemia Study) on a sole source basis from Batelle Memorial Institute, 505 King Avenue, Columbus, OH 43201, United States. The purpose of this acquisition is to complete the analyses of dust samples in order to evaluate risk of childhood leukemia.
This acquisition will be processed in accordance with simplified acquisition procedures as stated in FAR Part 13.106-1(b)(1) and is exempt from the requirements of FAR Part 6. The North American Industry Classification System code is 541380 and the business size standard is $14.0 million.
Only one award will be made as a result of this solicitation. It will be awarded as a firm fixed price type contract.
It has been determined there are no opportunities to acquire green products or services for this procurement.
OEEB conducts studies of cancer and environmental exposures to pesticides. Residential herbicide use is a suspected risk factor for childhood leukemia; however, the specific chemicals that might be responsible for this association have not been completely evaluated. The DCEG plans to evaluate the association between levels of glyphosate in homes and the association with childhood leukemia risk among participants of a case-control study of childhood leukemia in California (the California Childhood Leukemia Study [CCLS]), which was conducted by the DCEG in collaboration with University of California Berkeley from 2001 through 2007. Dust samples were collected in a second home interview for residentially stable cases and controls ages 0-7 years of age diagnosis (similar reference date for controls).
Prior analyses of pesticides in the dust samples did not include measurement of glyphosate, a herbicide used in many lawn treatment products and on agricultural crops. A recent evaluation by the International Agency for Research on Cancer determined that glyphosate is probably carcinogenic to humans based on epidemiology and mechanistic studies. In prior analyses of dust samples from this study by the DCEG, five (5) herbicides were measured including 2,4-D, MCPA, dicamba, dacthal, and simazine but only dacthal was associated with leukemia risk. Because self-reported treatment of lawn weeds was associated with increased risk of acute lymphoblastic leukemia (ALL) in this study population and because glyphosate is the second most common herbicide found in products for treating lawn and garden areas in this study population (after 2,4-D), the DCEG intends to measure glyphosate levels in homes in order to evaluate the relationship with ALL. In the first phase of this study it was found that glyphosate was detected in over 80% of homes. DCEG plans to analyze an additional 89 samples to increase our power to evaluate childhood leukemia risk and to evaluate determinants of glyphosate levels in homes.
The California Childhood Leukemia study was conducted in 35 counties in California and glyphosate was the one major pesticide that was not previously measured in dust samples from the homes of cases and controls. Accurately measured levels of pesticides and chemicals in the homes are critical to properly assess these exposures as risk factors for childhood leukemia. Battelle Memorial Institute is proposed as the laboratory to conduct the glyphosate measurements for this procurement. Battelle Memorial Institute conducted all the prior analysis of dust samples for over 40 pesticides and other chemicals with good quality control results and low detection limits. Battelle has extensive and unique experience in the measurement of glyphosate in house dust samples from large studies that is not available from any other potential contract source. They are in a unique position to conduct the work because they are the only known laboratory with the demonstrated expertise and experience to conduct these measurements. They actively developed and tested the methodology to measure glyphosate in house dust samples as part of their research program.
This notice is not a request for competitive quotation. However, if any interested party, especially small businesses, believes it can meet the above requirement, it may submit a capability statement, proposal, or quotation, which shall be considered by the agency. The statement of capabilities and any other information furnished must be in writing and must contain material in sufficient detail to allow NCI to determine if the party can perform the requirement. Responses must be received in the contracting office by 12:00 PM EST, on September 2, 2016. All responses and questions can be emailed to Kimesha Leake, Contract Specialist via electronic mail at kimesha.leake@nih.gov. A determination by the Government not to compete this proposed requirement based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. In order to receive an award, contractors must be registered and have valid certification in the System for Award Management (SAM) through sam.gov. Reference: N02RC62644-24 on all correspondence.
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9609 Medical Center Drive, Room 1E128
Source: https://www.fbo.gov/index?s=opportunity&mode=form&id=29aeef7bb9269a79644617045824c71c&tab=core&_cview=0 Rockville, Maryland 20852 United States
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